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US-market 2006–2015 Lexus IS250 sedans use the 2.5L 4GR-FSE and a replaceable cartridge element in a filter housing, not a spin-on can filter. The cartridge itself has no mounting thread or spin-on gasket: its O-ring seals the housing, while the drain-plug crush washer is a separate service part. Parts catalogues distinguish 04152-YZZA3 and 04152-YZZA5 applications (commonly listed RWD/AWD respectively), so use VIN/year/drivetrain lookup rather than an IS350 listing or an assumed thread size.
| # | Product | Price | Where to buy |
|---|---|---|---|
| 1 | Lexus/Toyota 04152-YZZA3 | $7–$15 | Amazon · eBay |
| 2 | Lexus/Toyota 04152-YZZA5 | $8–$18 | Amazon · eBay |
| 3 | Denso 150-3020 | $7–$15 | Amazon |
| 4 | WIX 57173 | $9–$18 | Amazon |
| 5 | WIX XP 57173XP | $12–$22 | Amazon |
| 6 | FRAM Endurance FE10158 | $10–$18 | Amazon |
| 7 | FRAM Tough Guard TG10158 | $8–$16 | Amazon |
| 8 | K&N HP-7023 | $12–$22 | Amazon |
| 9 | Bosch 3972 | $8–$16 | Amazon · eBay |
| 10 | Mobil 1 M1C-154A | $12–$22 | Amazon |
The picks, in detail
Lexus/Toyota 04152-YZZA3
Genuine cartridge element cross-referenced for IS250 applications; confirm VIN and RWD/AWD before ordering.
- cartridge element
- 2.5L 4GR-FSE lookup
- housing O-ring service
- OEM-number route
- not a reseller duplicate
- not a spin-on filter
- drivetrain lookup required
Lexus/Toyota 04152-YZZA5
Genuine cartridge-element number commonly catalogued for IS250 AWD applications; confirm against VIN.
- cartridge element
- 2.5L 4GR-FSE lookup
- additional housing-drain O-ring kit format
- OEM-number route
- separate service-kit reference
- not interchangeable by assumption
- not a threaded can
Denso 150-3020
Denso cartridge alternative cross-referenced to Toyota/Lexus 04152-YZZA3/YZZA5 family; use VIN fitment.
- cartridge element
- Toyota/Lexus cross-reference
- housing seal application
- distinct manufacturer
- cross-reference published
- not a spin-on
- verify drive layout
WIX 57173
WIX cartridge listed for the 2006 IS250 2.5L 4GR-FSE lookup.
- cartridge element
- 2006 2.5L lookup
- housing-fit design
- distinct filter maker
- specific WIX number
- not a threaded can
- confirm later-year VIN
WIX XP 57173XP
XP-branded WIX version cross-referenced for the 2006–2013 IS250 4GR-FSE application.
- cartridge element
- 4GR-FSE cross-reference
- XP product line
- specific XP SKU
- not a reseller relabel
- not a spin-on
- verify exact year
FRAM Endurance FE10158
FRAM Endurance cartridge cross-reference listed for 2006–2013 IS250 4GR-FSE.
- cartridge element
- 4GR-FSE cross-reference
- Endurance line
- specific FRAM SKU
- distinct filter line
- not a threaded can
- not an IS350 shortcut
FRAM Tough Guard TG10158
FRAM Tough Guard cartridge number listed in IS250 cross-reference material; verify VIN before purchase.
- cartridge element
- specific FRAM SKU
- housing seal service
- separate product line
- published cross-reference
- not a spin-on
- drivetrain still matters
K&N HP-7023
K&N cartridge cross-reference listed for 2006–2013 IS250 4GR-FSE, not a generic IS350 recommendation.
- cartridge element
- 4GR-FSE cross-reference
- specific K&N SKU
- distinct manufacturer
- specific number
- not a threaded can
- confirm VIN
Bosch 3972
Bosch cartridge cross-reference listed for the 2006–2013 IS250 2.5L application.
- cartridge element
- 2.5L 4GR-FSE cross-reference
- specific Bosch SKU
- distinct manufacturer
- specific number
- not a spin-on
- confirm exact model year
Mobil 1 M1C-154A
Mobil 1 cartridge cross-reference listed for 2006–2013 IS250 4GR-FSE fitment.
- cartridge element
- 4GR-FSE cross-reference
- specific Mobil 1 SKU
- distinct product line
- specific number
- not a threaded can
- verify VIN and drivetrain
Buying tips
- Confirm 2.5L 4GR-FSE, year and drivetrain by VIN; do not use IS350 fitment as a substitute.
- Replace the housing O-ring correctly and use a new drain-plug washer when specified; neither is a spin-on gasket.
- Use the housing-cap torque procedure from the service information, not a thread specification copied from a can filter.
As an Amazon Associate and eBay Partner, toptenpick.com earns from qualifying purchases. Prices and availability are subject to change.